This study is a descriptive research study to confirm the care efficacy and empathy competency of nursing hospital nurses and analyze the factors to improve person-centered care behavior, provide theoretical and practical information accordingly, and prepare basic data. The study collected data from March 20, 2023 to April 20, 2023, targeting 146 nurses at a nursing hospital for the elderly in C region located in G province, and finally analyzed a total of 144 copies. Using IBM SPSS/25, descriptive statistics t-test, ANOVA, and correlation multiple regression analysis were analyzed. As a result of analyzing the variables that affect the subject's person-centered care by hierarchical multiple regression, the higher the caring efficacy and empathy capacity, the more the person-centered care was affected, and the explanatory power was 31.5%. As a result of this study, empathy competency and care efficacy were found to have an effect on person-centered care. It is thought that various measures should be prepared to improve the care efficacy and empathy competency for the efficient nursing performance of person-centered care of nursing hospital nurses.