Purpose: The purpose of this study is to examine the relationships among job stress, resilience and turn over intention of new graduate nurses in general hospital. Methods: A descriptive regression design was used and the participants were 90 new graduate nurses from one general hospital in S city. Data analysis included t-test, ANOVA, pearson's correlation and multiple regression. Results: There were significant correlations between conflict with physicians(r=.17, p=.049), problem relating to supervisors(r=.18, p=.040), discrimination(r=.18, p=.041), resilience(r=-.21, p=.023) and turnover intention. The regression model explained approximately 24.5 % of turnover intention. Conclusion: The findings suggest that nursing leaders have to reduce job stress and to improve resilience of new graduate nurses.