Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
- Resource Type
- Short Communication
- Authors
- Labadie, Sharada; Dragovich, Peter S.; Barrett, Kathy; Blair, Wade S.; Bergeron, Philippe; Chang, Christine; Deshmukh, Gauri; Eigenbrot, Charles; Ghilardi, Nico; Gibbons, Paul; Hurley, Christopher A.; Johnson, Adam; Kenny, Jane R.; Kohli, Pawan Bir; Kulagowski, Janusz J.; Liimatta, Marya; Lupardus, Patrick J.; Mendonca, Rohan; Murray, Jeremy M.; Pulk, Rebecca; Shia, Steven; Steffek, Micah; Ubhayakar, Savita; Ultsch, Mark; van Abbema, Anne; Ward, Stuart; Zak, Mark
- Source
- In Bioorganic & Medicinal Chemistry Letters 15 December 2012 22(24):7627-7633
- Subject
- Language
- ISSN
- 0960-894X