Difference between Alzheimer’s Disease and Mild Cognitive Impairment: Z-test based Study
- Resource Type
- Conference
- Authors
- Chandra, Abhijit; Roy, Subhabrata
- Source
- 2021 IEEE 2nd International Conference on Applied Electromagnetics, Signal Processing, & Communication (AESPC) Applied Electromagnetics, Signal Processing, & Communication (AESPC), 2021 IEEE 2nd International Conference on. :1-5 Nov, 2021
- Subject
- Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Fields, Waves and Electromagnetics
Power, Energy and Industry Applications
Robotics and Control Systems
Signal Processing and Analysis
Cerebellum
Fluids
Statistical analysis
Sociology
Grey matter
Cerebrum
Indexes
Alzheimer’s disease (AD)
asymmetry index
cerebrospinal fluid (CSF)
grey matter (GM)
mild cognitive impairment (MCI)
white matter (WM)
z-test
- Language
Anatomical composition of human brain gets seriously affected by a variety of neurodegenerative disease including Alzheimer’s disease (AD). Research work is being carried out throughout the globe to identify those primary elements which may serve as indicators for the diagnosis of these diseases. In this communication, a statistical analysis has been performed to figure out the essential parameters on the basis of which AD and mild cognitive impairment (MCI) can be distinguished. Five such parameters are considered for the proposed analysis using z-test. It has been observed that there exist significant differences between the AD and MCI samples in terms of three such parameters namely volume of white matter, grey matter and cerebrospinal fluid. It is also concluded that asymmetry index in cerebrum and cerebellum do not exhibit critical impact as far as the difference between AD and MCI is concerned.