Objective: To investigate the changes of ankle-brachial index (ABI) and peak velocity of dorsal foot artery in patients with type 2 diabetes mellitus with lower extremity vascular disease treated with Yingweifang. Methods: 36 cases of type 2 diabetes mellitus with lower extremity vascular disease were observed, including 13 cases of Yin deficiency and hot, 9 cases of qi and Yin deficiency and 14 cases of Yin and Yang deficiency. Oral “Yingwei Fang” capsule, 5 capsules per time, 3 times a day, combined with the dialectical TCM dialectical theory of treatment, conventional treatment such as hypoglycemia. Changes in the ankle-brachial index (ABI) and peak flow rate of dorsal foot artery were measured after 150 days of treatment compared with before treatment. RESULTS: After treatment, ABI and peak flow rate of dorsal foot artery in diabetic lower extremity vascular disease patients were changed in different degrees (P < 0.05, P