Enterprise evaluation is a specialized activity derived with the development of economy, but in the process of enterprise evaluation, much changes will affect the appraisal results and reduce the accuracy of appraisal. This paper proposes a genetic contraindication algorithm to analyze the evaluation method, can the level of enterprise evaluation, and shorten the formulation time of the evaluation method. Then, a comprehensive evaluation of the real data is conducted. Finally, continuous monitoring is used for the evaluation method, and the final evaluation results are output. The results show that the genetic contraindication algorithm can accurately perform enterprise evaluation. Improve the level of evaluation methods, and the accuracy is greater than 95%, which is better than the traditional algorithm. Tabu algorithm can constrain enterprise evaluation and prediction, reduce external interference and improve the accuracy of prediction. Therefore, the genetic contraindication algorithm can meet the requirements of enterprise evaluation and is suitable for continuous analysis of enterprise evaluation. Compared with traditional methods, genetic taboo can improve the accuracy of calculation results, and make its accuracy more than 90%. At the same time, genetic tabu algorithm can meet the actual needs of enterprise evaluation, and better track evaluation and analysis.