With the rapid development of enterprises information system, many hackers illegally obtain enterprise information through exploiting information system vulnerabilities, which caused huge economic losses to enterprise, therefore, vulnerability scanning and governance system has become an indispensable part of enterprises information security. This paper proposes a vulnerability scanning method based on public vulnerability information, and designs a fast cross-regional vulnerability management platform which realizes the discovery and processing of high-risk vulnerabilities in the information system of production control area and management control area. This platform can finish a comprehensive detect on system of production control area and management information area, which notably improves the vulnerability management efficiency and the enterprise asset security.