Electric vehicle supply infrastructures represent a valid mean to integrate and encourage electric mobility, ensuring safe integration of electric vehicle (EV), renewable sources, and controllable devices. Management of these infrastructures under DC microgrid framework is affected by EV usage pattern, involving stochastic features, and by vehicle-to-grid ability, yielding the need of suitable operation strategy assessment. This article is focused on the analyses of day-ahead performances of a DC microgrid based on the solution of different optimization algorithms, involving technical and economic targets. The study involves statistical analyses concerning EVs usage, based on historical dataset, with the aim to generate scenarios to be investigated. Performances are compared by means of technical and economic indicators. The considered layout of DC microgrid refers to a realistic installation.