Implementation of Shear Wave and Strain Elastography with Micro-Ultrasound
- Resource Type
- Conference
- Authors
- Aleef, Tajwar Abrar; Vassallo, Reid; Zeng, Qi; Mahdavi, S. Sara; Wodlinger, Brian; Mannas, Miles; Black, Peter C.; Salcudean, Septimiu E.
- Source
- 2023 IEEE International Ultrasonics Symposium (IUS) Ultrasonics Symposium (IUS), 2023 IEEE International. :1-6 Sep, 2023
- Subject
- Bioengineering
Components, Circuits, Devices and Systems
Fields, Waves and Electromagnetics
Signal Processing and Analysis
Quality assurance
Tracking
Imaging
Phantoms
Elasticity
Hardware
Acoustics
micro-ultrasound
prostate cancer
targeted biopsy
shear wave elastography
strain elastography
- Language
- ISSN
- 1948-5727
Quantitative tissue stiffness characterization can aid in diagnosing prostate cancer. Shear wave absolute vibro-elastography (S-WAVE) provides quantitative, multi-frequency shear wave imaging with external excitation, while strain elastography (SE) provides a map of relative tissue stiffness. In this work, we present a first-of-its-kind micro-ultrasound (microUS)-based system for prostate elastographic imaging. The system uses an ExactVu™ microUS with minimum hardware addition– making it compatible with the current clinical workflow. Bandpass sampling is utilized to effectively recreate phasors with a frame rate beneath the Nyquist sampling rate for tissue motion tracking in S-WAVE imaging. We characterize the methods (S-WAVE and SE) with a commercial quality assurance elasticity phantom having inclusions with different levels of stiffness. Promising results are achieved with both methods being able to identify all four inclusions with their expected contrast difference.