Mouse embryo assay to evaluate polydimethylsiloxane (PDMS) embryo-toxicity
- Resource Type
- Conference
- Authors
- Colucci, F.; McKeegan, P.; Picton, H.M.; Pensabene, V.
- Source
- 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) IEEE Engineering in Medicine and Biology Society (EMBC), 2018 40th Annual International Conference of the. :4484-4487 Jul, 2018
- Subject
- Bioengineering
Embryo
Microfluidics
Mice
Standards
In vitro
Subspace constraints
Oils
- Language
- ISSN
- 1558-4615
In vitro embryo culture to support In Vitro Fertilization (IVF) procedures is a well-established but still critical technique. In the last decade first attempts to use microfluidic devices in IVF have shown positive results, enabling to control the culture conditions and to preserve the quality of the embryos during their development. In this study we completed an industry standard mouse embryo assay (MEA) to exclude potential toxic effects of PDMS.