This paper explores the significant impact of smart production on human resource empowerment and opportunity seizing. Smart production is a technological transformation that integrates advanced technologies like computer aided manufacturing, artificial intelligence, machine learning, robotics, and the internet of things. The research findings provide empirical evidence that smart production can facilitate human resource empowerment which literally means providing employees with the necessary tools, skills, and knowledge to perform their jobs efficiently, increase their income and well-being, and reduce labour accidents. Smart production also open up new business opportunities, enabling businesses to find customers in other market segments.