Numerical Modeling of MR Angiography for Quantitative Validation of Image-Driven Assessment of Carotid Stenosis
- Resource Type
- Periodical
- Authors
- Klepaczko, A.; Materka, A.; Szczypinski, P.; Strzelecki, M.
- Source
- IEEE Transactions on Nuclear Science IEEE Trans. Nucl. Sci. Nuclear Science, IEEE Transactions on. 62(3):619-627 Jun, 2015
- Subject
- Nuclear Engineering
Bioengineering
Blood
Magnetization
Mathematical model
Computational modeling
Angiography
Numerical models
Carotid artery stenosis
computational fluid dynamics
image-based medical diagnosis
magnetic resonance angiography
MRI simulation
vessel segmentation
- Language
- ISSN
- 0018-9499
1558-1578
In this paper we present a numerical framework for validating methods of quantitative analysis of non-invasive MR angiography imaging protocols such as Time-of-Flight (ToF) and Phase Contrast Angiography (PCA). Our study is motivated by the need to reliably and objectively verify blood flow and geometry measurements derived from image data. Both factors are important predictors in diagnosing of carotid artery stenosis. Credibility of the tested image processing methods is verified by comparing their results against reference models designed using integrated flow and MRA imaging simulator.