Attomolar streptavidin and pH, low power sensor based on 3D vertically stacked SiNW FETs
- Resource Type
- Conference
- Authors
- Buitrago, Elizabeth; Fernandez-Bolanos, Montserrat; Georgiev, Yordan M.; Ran Yu; Lotty, Olan; Holmes, Justin D.; Nightingale, Adrian M.; Ionescu, Adrian M.
- Source
- Proceedings of Technical Program - 2014 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA) VLSI Technology, Systems and Application (VLSI-TSA), Proceedings of Technical Program - 2014 International Symposium on. :1-2 Apr, 2014
- Subject
- Components, Circuits, Devices and Systems
Computing and Processing
Photonics and Electrooptics
Signal Processing and Analysis
Logic gates
Three-dimensional displays
Sensors
Field effect transistors
Dielectrics
Periodic structures
Sensitivity
- Language
- ISSN
- 1524-766X
3D vertically stacked silicon nanowire (SiNW) field effect transistors (FET) with high density arrays (up to 7×20) of fully depleted and ultra-thin (15–30 nm) suspended channels were fabricated by a top-down CMOS compatible process on silicon on insulator (SOI). The channels can be wrapped by conformal high-κ gate dielectrics (HfO 2 ) and their conductivity can be excellently controlled either by a reference electrode or by three local gates; a backgate (BG) and two symmetrical Pt side-gates (SG) offering unique sensitivity tuning. Such 3D structure has been (3-Aminopropyl)-triethoxysilane (APTES) functionalized and biotynilated for pH and streptavidin (protein) sensing, respectively. An ultra-low concentration of 17 aM of streptavidin was measured, the lowest ever reported in literature. Extremely high quasi-exponential drain current responses (ΔI d /pH) of ∼0.70 dec/pH were measured for structures with APTES functionalized SiO 2 gate dielectrics when operated in the subthreshold regime. Also, high drain current responses > 20 µA/pH and high sensitivities (S ∼ 95%) were measured for structures with a native oxide gate dielectrics when operated in the strong-inversion regime.