The development of Micro, Small and Medium Enterprises (MSMEs) in Indonesia is growing rapidly every year. So this has an impact on the narrowness of the business location to be chosen. Accuracy in determining the location of the business will affect the success or failure of the business. So we need an analysis using the Multi Attribute Decision Making (MADM) method. In this study, the methods used were Multifactor Evaluation Process (MFEP) and Simple Additive Weighting (SAW). There are 3 alternative locations that are assessed, and there are 9 factors or criteria that support the assessment of each decision support alternative. The final result of the calculation is the first alternative (MFEP = 6.30; SAW = 0.82), the second alternative (MFEP = 7.60; SAW = 0.98), and the third alternative (MFEP = 6.90; SAW = 0.90). The results of the comparative analysis conclude that the two methods have the same rank, where the second alternative has the highest value so that it becomes the most strategic business location alternative.