A Setup for Conduction Velocities and Temperature Gradients Measurements during Infrared Neurostimulation
- Resource Type
- Conference
- Authors
- Perre, Louis Vande; Cury, Joaquin; Cerda, Javier Chavez; Verstraeten, Maxime; Raffoul, Romain; Doguet, Pascal; Delbeke, Jean; Tahry, Riem El; Gorza, Simon-Pierre; Nonclercq, Antoine
- Source
- 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) Biomedical Circuits and Systems Conference (BioCAS), 2022 IEEE. :453-457 Oct, 2022
- Subject
- Bioengineering
Temperature measurement
Optical fibers
Biomedical optical imaging
Action potentials
Stimulated emission
Biomedical measurement
Optical variables measurement
Infrared Neural Stimulation
conduction velocity
ex vivo Rat Sciatic Nerve
- Language
Infrared Neural Stimulation (INS) is a novel neuromodulation technique involving a rapid temperature increase of the neuron membrane, resulting in action potential triggering. This paper describes an experimental setup developed to measure the spatiotemporal temperature gradients at the surface of an ex vivo sciatic nerve. The setup is also designed to measure the conduction velocity of the nervous fibers excited by INS, with the aim of determining the type of fibers activated during optical stimulation. Two animal experiments successfully validated the setup and provided encouraging results on (1) the impact of heat accumulation on INS and (2) the difference in nerve fibers excited by optical and electrical nerve stimulation.