In this paper, we propose and investigate a new scheme, which is referred to as extended enhanced spatial modulation (EESM). In the EESM system, the spatial constellation vectors are exploited by utilizing both active antennas and multiple signal constellations. The advantage is that it can enhance the spectral efficiency as well as the reliability of transmission with the aid of the signal and space domains. Furthermore, the average bit error probability (BEP) are analyzed. Simulation results demonstrate that the lower BEP can be achieved by the EESM than existing spatial modulation schemes.