Addition of gadolinium contrast to three-dimensional SSFP MR sequences improves the visibility of coronary artery anatomy in young children
- Resource Type
- article
- Authors
- Quanli Shen; Chengxiang Lin; Qiong Yao; Junbo Wang; Jian Zhou; Lan He; Gang Chen; Xihong Hu
- Source
- Frontiers in Pediatrics, Vol 11 (2023)
- Subject
- magnetic resonance coronary angiography
whole heart
steady-state free precession
contrast media
children
Pediatrics
RJ1-570
- Language
- English
- ISSN
- 2296-2360
ObjectiveThis study aims to compare the value of a gadolinium contrast-enhanced 1.5-T three-dimensional (3D) steady-state free precession (SSFP) sequence with that of a noncontrast 3D SSFP sequence for magnetic resonance coronary angiography in a pediatric population.Materials and methodsSeventy-nine patients from 1 month to 18 years old participated in this study. A 3D SSFP coronary MRA at 1.5-T was applied before and after gadolinium-diethylenetriaminepentaaceticacid (DTPA) injection. The detection rates of coronary arteries and side branches were assessed by McNemar's χ2 test. The image quality, vessel length, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the coronary arteries were analyzed by the Wilcoxon signed-rank test. The intra- and interobserver agreements were evaluated with a weighted kappa test or an intraclass correlation efficient test.ResultsA contrast-enhanced scan detected more coronary arteries than a noncontrast-enhanced scan in patients under 2 years old (P 0.05). The contrast-enhanced 3D SSFP protocol detected longer lengths for the left anterior descending coronary artery in children younger than 2 years and the left circumflex coronary artery (LCX) in children younger than 5 years (P