Along with the industrialization and popularization of the wearable electronics, an increasing number of the wireless sensor nodes (WSNs) are deployed. Nevertheless, the conventional battery-based power supply system has no longer satisfied the requirement of large-scale WSNs in terms of battery life, which emerges the energy harvesting (EH) technique. In order to combine various of energy sources and drive multi-loads, the multi-input single-inductor multi-output (MISIMO) EH interface applied to wearable electronics is spotlighted. In this mini-review article, the solutions for improving power conversion efficiency (PCE) and output quality in MISIMO EH interface are summarized. Furthermore, the future trends of MISIMO EH interface are also presented.