Considering the tracking deviation of the linear variable parameter networked control system(NCS) under a deception attack with unknown statistical characteristics, a novel control strategy based on set-membership estimation was proposed to realize the effective tracking of the system state to the reference system state. Firstly, compared to methods such as the Kalman estimation with the known statistical characteristics of the attack in advance, a novel set-membership estimation was proposed to improve the accuracy and application scope of the estimation, in which the deception attack suffered in the sensor-to-controller channel and the controller-to-actuator channel only needed to be modeled as an unknown but bounded(UBB) signal, and to guarantee that the true state and estimated state of the system consisted in the estimated set. Secondly, the sufficient conditions for the stability of the error closed-loop system based on the Lyapunov function were given. Simultaneously, the solving algorithm of the estimator and the controller based on the linear matrix inequality was obtained, and the convex optimization method was adopted to achieve the best estimation set. Finally, the feasibility of the proposed method was verified by numerical simulation.