Impact of adherence to guideline‐directed therapy on risk of death in HF patients across an ejection fraction spectrum
- Resource Type
- article
- Authors
- Xiaojing Chen; Yu Kang; Ulf Dahlström; Michael Fu
- Source
- ESC Heart Failure, Vol 10, Iss 6, Pp 3656-3666 (2023)
- Subject
- Heart failure
Left ventricular ejection fraction
Guideline‐directed medical therapy
All‐cause mortality
Diseases of the circulatory (Cardiovascular) system
RC666-701
- Language
- English
- ISSN
- 2055-5822
Abstract Aims How different degrees of adherence to guideline‐directed medical therapy (GDMT) affect mortality risk in patients with heart failure (HF) in a real‐world clinical setting is poorly understood. This study sought to investigate how different levels of adherence to GDMT were associated with the risk of all‐cause mortality in patients with HF across a spectrum of left ventricular ejection fractions (LVEFs) in a real‐world clinical setting. Methods and results A total of 64 610 HF patients with no missing value of LVEF from the Swedish Heart Failure Registry were included in the study. Patients were divided according to different LVEFs (