Malignant catatonia and neuroleptic malignant syndrome in relation to disulfiram overdose
- Resource Type
- article
- Authors
- Kiran K Kumar; Swapna Bondade; Fiaz Ahmed Sattar; Niharika Singh
- Source
- Indian Journal of Psychological Medicine, Vol 38, Iss 4, Pp 344-347 (2016)
- Subject
- Disulfiram
malignant catatonia
neuroleptic malignat syndrome
Psychiatry
RC435-571
- Language
- English
- ISSN
- 0253-7176
Disulfiram is a widely used drug in the management of alcohol dependence syndrome as an aversive agent. Although a drug of high efficacy, it has a large number of side effects. Disulfiram-induced catatonia is a known rare side effect of the drug and herein we report a case of what appeared to be the sequential development of malignant catatonia and neuroleptic malignant syndrome in a patient with a diagnosis of alcohol dependence syndrome and co-morbid paranoid schizophrenia following disulfiram overdose. Clinicians need to be vigilant on the emergence of such rare side effects.