Impact of Cardiac Contractility during Cerebral Blood Flow in Ischemia
- Resource Type
- article
- Authors
- Silver, Brian; Lewandowski, Christopher; Rivers, Emanuel; Wira, Charles
- Source
- Western Journal of Emergency Medicine, Vol 12, Iss 2, Pp 227-232 (2011)
- Subject
- stroke
cerebral vascular accident
transient ischemic attack
ejection fraction
cerebral blood flow
Medicine
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
- Language
- English
- ISSN
- 1936-900X
1936-9018
Objective: In cerebral regions affected by ischemia, intrinsic vascular autoregulation is often lost. Blood flow delivery depends upon cardiac function and may be influenced by neuro-endocrine mediated myocardial suppression. Our objective is to evaluate the relation between ejection fraction (EF) and transcranial doppler (TCD) peak systolic velocities (PSV) in patients with cerebral ischemic events.Methods: We conducted a retrospective cohort study from an existing TCD registry. We evaluated patients admitted within 24 hours of onset of a focal neurological deficit who had an echocardiogram and TCD performed within 72 hours of admission.Results: We identified 58 patients from March to October 2003. Eighty-one percent (n=47) had a hospital discharge diagnosis of ischemic stroke and 18.9% (n=11) had a diagnosis of transient ischemic attack. Fourteen patients had systolic dysfunction (EF50%) compared to those with systolic dysfunction (EF