Soil salinity is a critical environmental problem especially in arid and semiarid regions. Then, the objective of this study is to detect saline soils by synergistic use of the Advanced Microwave Scanning Radiometer 2 (AMSR2) and the Moderate Resolution Imaging Spectroradiometer (MODIS) images. In this regard, the Total Precipitable Water (TPW) Vapor parameter obtained from AMSR2 and MODIS, the Microwave Polarization Difference Index (MPDI), and a vertical to horizontal brightness temperature ratio ($TB_{v}/TB_{h}$) in the 6 GHz channel of AMSR2 were used in two procedures. In procedure 1, the thresholding on the TPW and MPDI, and in procedure 2, the thresholding on the TPW and the $TB_{v}/TB_{h}$ in the 6 GHz channel were investigated. The overall accuracy and Kappa coefficient of the produced saline soil map by the procedure 1 were acquired as 0.865 and 0.715, and for the procedure 2 were 0.809 and 0.607, respectively.