Elevated serum homocysteine levels associated with poor recurrence-free and overall survival in patients with colorectal cancer
- Resource Type
- article
- Authors
- Hailun Xie; Lishuang Wei; Qiwen Wang; Shuangyi Tang; Jialiang Gan
- Source
- Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
- Subject
- Malnutrition
Homocysteine
Nomogram
Colorectal cancer
Prognostic
Medicine
Science
- Language
- English
- ISSN
- 2045-2322
Abstract This study aimed to evaluate the significance of homocysteine (HCY) levels in predicting recurrence-free survival (RFS) and overall survival (OS) in colorectal cancer (CRC) patients. This retrospective study involved 1272 CRC patients. The risk of mortality increased with increasing HCY levels in CRC patients. The optimal HCY cutoff value in CRC patients was 15.2 μmol/L. The RFS (45.8% vs. 60.5%, p