Alpha blocker prazosin for the treatment of benign prostatic hypertrophy (BPH).
- Resource Type
- article
- Authors
- Punekar S; Kelkar A; Gavande P; Rao N; Date J; Prem A
- Source
- Journal of Postgraduate Medicine, Vol 41, Iss 4, Pp 99-101 (1995)
- Subject
- Adrenergic alpha-Antagonists
therapeutic use
Comparative Study
Human
Male
Prazosin
Prostatic Hyperplasia
drug therapy
surgery
Transurethral Resection of Prostate
Treatment Outcome
Urination
physiology
Medicine
- Language
- English
- ISSN
- 0022-3859
0972-2823
In this study medical treatment with alpha blocker-prazosin is compared with transurethral resection of prostate (TURP) in 62 patients suffering from benign enlargement of prostate with a gland size of less than 20 gms. After thorough interrogation patients were offered either TURP or prazosin therapy. Symptom scoring, residual volume of urine and urinary flow rates were estimated in both the groups before and 3 months after the therapy. 23.5% patients in prazosin group while 90% of patients in TURP group had significant improvement. This distinctly brings out the superiority of TURP for benign enlargement of prostate.