The level of partial pressure of carbon dioxide affects respiratory effort in COVID-19 patients undergoing pressure support ventilation with extracorporeal membrane oxygenation
- Resource Type
- article
- Authors
- Yuankai Zhou; Xinchen Wang; Wei Du; Huaiwu He; Xiaoting Wang; Na Cui; Yun Long
- Source
- BMC Anesthesiology, Vol 24, Iss 1, Pp 1-8 (2024)
- Subject
- PaCO2
COVID-19
Respiratory effort
Extracorporeal membrane oxygenation
Anesthesiology
RD78.3-87.3
- Language
- English
- ISSN
- 1471-2253
Abstract Background Patients with COVID-19 undergoing pressure support ventilation (PSV) with extracorporeal membrane oxygenation (ECMO) commonly had high respiratory drive, which could cause self-inflicted lung injury. The aim of this study was to evaluate the influence of different levels of partial pressure of carbon dioxide(PaCO2) on respiratory effort in COVID-19 patients undergoing PSV with ECMO. Methods ECMO gas flow was downregulated from baseline (respiratory rate