Rapid prototyping and design of cybergenetic single-cell controllers
- Resource Type
- article
- Authors
- Sant Kumar; Marc Rullan; Mustafa Khammash
- Source
- Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
- Subject
- Science
- Language
- English
- ISSN
- 2041-1723
Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.