STAT5 and CD4+ T Cell Immunity [version 1; referees: 4 approved]
- Resource Type
- article
- Authors
- David L. Owen; Michael A. Farrar
- Source
- F1000Research, Vol 6 (2017)
- Subject
- Autoimmunity
Innate Immunity
Leukocyte Development
Leukocyte Signaling & Gene Expression
Medicine
Science
- Language
- English
- ISSN
- 2046-1402
STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4+ helper and regulatory T-cell subsets.