Case report and literature review: A thyroid storm patient with severe acute hepatic failure treated by therapeutic plasma exchange and a double plasma molecular absorption system
- Resource Type
- article
- Authors
- Fuquan Tu; Yiqin Lin; Junnian Chen; Lili Zhou; Liyong Lin; Qin Liu; Wenwei Wu
- Source
- Heliyon, Vol 10, Iss 7, Pp e28867- (2024)
- Subject
- Thyroid storm
Acute hepatic failure
Therapeutic plasma exchange
Double plasma molecular absorption system
Case report
Science (General)
Q1-390
Social sciences (General)
H1-99
- Language
- English
- ISSN
- 2405-8440
Thyroid storm (TS) leading to acute liver failure is rare but fatal in clinical practice and hepatic failure can remarkably limit medication options for TS. We successfully cured a patient with TS complicated with acute hepatic failure using therapeutic plasma exchange (TPE) and a double plasma molecular absorption system (DPMAS) and summarized the case characteristics of 10 similar critical patients reported worldwide. We recommend that patients with TS complicated with liver failure disuse propylthiouracil or methimazole. TPE should be utilized to rapidly decrease thyroid hormone levels, and DPMAS should be considered for supportive treatment in the presence of hepatic encephalopathy or dramatic bilirubin elevations.