Geminal group-directed olefinic C-H functionalization via four- to eight-membered exo-metallocycles
- Resource Type
- article
- Authors
- Keke Meng; Tingyan Li; Chunbing Yu; Cong Shen; Jian Zhang; Guofu Zhong
- Source
- Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
- Subject
- Science
- Language
- English
- ISSN
- 2041-1723
Identifying distinct cyclometallation pathways is essential to new types of C-H activation and functionalization in organic synthesis. Here, the authors show the activation of an olefinic C-H bond geminal to the directing group via four- to eight-membered exo-palladacycles with broad substrate scope.