Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents
- Resource Type
- article
- Authors
- Aysel Veysioğlu; Şükriye Çakmak
- Source
- Hittite Journal of Science and Engineering, Vol 7, Iss 4, Pp 345-351 (2020)
- Subject
- amides
secondary amides
n-acylation
antimicrobial activity
characterization
Engineering (General). Civil engineering (General)
TA1-2040
- Language
- English
- ISSN
- 2148-4171
The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides. All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis. Antimicrobial activities of the molecules were evaluated against various bacterial and fungal species. The results show that the some new compounds exhibit good antibacterial and antifungal activities.