Different routes can be used to produce the PET isotope 68Ga by proton reactions on different targets. The experimental excitation functions for the reactions 68Zn(p, n) and 72Ge(p, nα) were collected from previous studies and compared with each other, for each reaction, in order to get the most trusted data. Some data were excluded because they gave either too high or too low cross section values. The others were averaged together to give a kind of trusted data set for the production of this important radioisotope. The production of the radionuclide 68Ge, used in the generator 68Ge/68Ga, through proton reactions was also discussed in the same manner. Model calculations of excitation functions of the above mentioned reactions were performed, using both TALYS-1.4 and EMPIRE-3.1 codes, and the results were compared with the averaged experimental data. Some statistical parameters were introduced to control the quality of the overlapping between experimental data and model calculations. The integrated yields for the different reactions leading to 68Ga were estimated. The various routes were discussed on the basis of the given results.