Industry 4.0 (I4.0) brings with it a series of changes in the companies; among them we find those that affect the business models to get the concept of smart factory. This change in business models implies a complete communication network between different companies, factories, suppliers, resources and others optimized in real time, so that maximum efficiency is achieved for all parties involved. The objective is in identifying a methodology that allows to define the supply chain (SC) that improves the performance and sustainability of the shipbuilding industry. Therefore, this chapter aims at connecting each of the key I4.0 technologies with the most significant SC paradigms: lean, agile, resilience and green to define what the shipbuilding SC should be. This study shows how each of the enabling technologies affects the SC, what paradigms to achieve and what steps to follow through the simulation of discrete events to end up implementing the shipbuilding supply chain in a 4.0 environment