CO2 reforming of CH4, also known as dry reforming of methane (DRM), is considered, nowadays, as an excellent option to produce H2 and CO (syngas) further used notably for the production of higher alkanes and oxygenates. Owing to their reasonable performances and economic advantages, nickel-based heterogeneous catalysts are considered as excellent candidates for DRM. However, these materials suffer from severe drawbacks such as sintering of the active phase and coke (carbon) deposition, which lead, in some cases, to sever deactivations. Several synthesis strategies, mostly based on the stabilization of nickel by an oxide support, have been developed in order to overcome those obstacles. Silica-based materials are widely investigated due to their availability, high surface area, and the confinement capacity brought by their controlled porosity. This review summarizes the progress made between 2015 and 2018 in the design of Ni-/silica-based catalysts for the dry reforming of methane. The different strategies implemented for the confinement and the control of nickel particles size will be discussed in the light of the performances of the resulting catalysts.