目的 分析过敏性紫癜(henoch-schonlein purpura,HSP)患儿维生素D含量的变化.方法 选取2022 年 7 月至 2023 年 7 月在昆明市儿童医院就诊,符合HSP诊断的 130 例患儿作为研究对象,正常对照组选取同时期在昆明市儿童医院儿保科体检的 100 例健康儿童.收集HSP患儿及正常对照组儿童的血液标本,经昆明金域医学检验所测定各组儿童血清 25(OH)D含量.结果 HSP患儿血清 25(OH)D含量较正常对照组儿童降低,差异有统计学意义(P<0.01);HSP患儿维生素D不足率较正常对照组增高,差异有统计学意义(P<0.01).结论 HSP患儿易出现维生素D不足,维生素D的补充可能为HSP的治疗提供新思路.
Objective To analyze the changes of vitamin D in children with Henoch-Schonlein purpura(HSP).Methods 130 children with HSP from Kunming Children's Hospital between July 2022-July 2023 were selected as the study subjects and 100 healthy children were selected during the same period as the control group.The blood samples were collected from the children with HSP and the healthy children.The content of vitamin D was measured by Kunming Kingmed Institute for Clinical Laboratory.Results The content of 25(OH)D in children with HSP was lower than that in healthy children,and the difference was statistically significant(P<0.01).The proportion of vitamin D insufficiency in children with HSP was higher than that in healthy children,and the difference was statistically significant(P<0.01).Conclusion The children with HSP are prone to vitamin D insufficiency.Vitamin D supplementation may provide a new method for the treatment of HSP.