[目的]探讨纪伟教授治疗强直性脊柱炎的临床经验.[方法]从病因病机、辨证施治等方面论述纪伟教授治疗强直性脊柱炎的学术观点和临床经验,对其谴方用药及中医调理方面的特色予以总结,并举案例佐证.[结果]纪伟教授认为强直性脊柱炎主要病机为肾虚督空,风、寒、湿、热、痰、瘀之邪痹阻经络,早中期当以祛风除湿、蠲痹通络为务,晚期则当以补肾强督、化痰散瘀为要.临证应四诊合参,详辨主次,注意川乌、附子、雷公藤等有毒药物的使用,以及乌梢蛇、全蝎、蜈蚣等虫类药的巧妙选用,并重视强直性脊柱炎合并炎性肠病、葡萄膜炎等兼夹证的治疗.所举案例,效益明显.[结论]纪伟教授治疗强直性脊柱炎的经验临床上行之有效,具有推广应用价值.
[Objective] To discuss Professor JI Wei's clinical experience in treating ankylosing spondylitis.[Methods] To expound Professor JI Wei's academic thoughts and clinical experience in ankylosing spondylitis from aspects of etiology,pathogenesis,and syndrome differentiation and treatment variation, summarizing the characteristics of her prescriptions and ways of treatment as well as exemplifying them. [Results] Professor JI Wei believes that the basic pathogenesis of this disease is kidney deficiency and governor vessel vacuity,with wind,coldness,dampness,heat,phlegm,and blood stasis obstructing channels and collaterals. In her opinion,the major task of the early- and middle-term of this disease is to dispel wind and eliminate dampness and to alleviate impediment and free the vessels,and that of the late-term is to supplement the kidney and reinforce the governor vessel and to transform phlegm and disperse blood stasis. When treating the disease,we should correlate all four examinations,differentiating carefully the primary from the secondary, paying attention to the unique use of aconitum,monkshood,triptolide and other toxic drugs,as well as the black snake,scorpion,centipede and other animal medicinals,and attaching importance to ankylosing spondylitis complicated with inflammatory bowel disease ,treatment of uveitis and syndrome. [Conclusion] Professor JI Wei's clinical experience in treating ankylosing spondylitis is effective and worthy of wide application.