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요약정보
临床常用抗抑郁药物不良反应研究进展 / Adverse Drug Reactions of Commonly Prescribed Antidepressants
Resource Type
Academic Journal
Authors
王先萍
;
刘丽容
;
罗琪丰
;
周欣萌
;
戚方怡
;
陈光
;
Wang Xianping
;
Liu Lirong
;
Luo Qifeng
;
Zhou Xinmeng
;
Qi Fangyi
;
Chen Guang
Source
台州学院学报 / Journal of Tanzhou University
. 44(6):71-77
Subject
抑郁症
抗抑郁药物
不良反应
Language
Chinese
ISSN
1672-3708
Online Access
Full Text (CAJ - 교육/사회)
초록
抑郁症是一种常见的精神障碍,发病率逐年升高,是全世界主要的致残原因之一,严重危害人类生命健康.药物治疗是治疗抑郁症的主要方法,三环类抗抑郁药是最早用于临床的抗抑郁药,四环类抗抑郁药与三环抗抑郁药作用效果相似,但均由于不良反应多且严重,现在已较少应用;单胺氧化酶抑制剂是另一类进入临床较早的抗抑郁药,因易导致五羟色胺综合症也较少应用;神经递质再摄取抑制剂等是临床最常用的新型抗抑郁药,不良反应较其他类别少而轻,但是儿童和青少年服用该类药物后可能出现自杀和自残念头,故儿童和青少年禁用,18~24岁年轻人慎用.药物不良反应发生率相对较高而且严重是限制抗抑郁药物临床应用的主要原因,本文综述了临床常用抗抑郁药物的不良反应,以期为该类药物合理应用于临床提供参考.
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