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요약정보
快速响应葡萄糖敏感微凝胶的制备及性能 / Synthesis and properties of rapidly glucose-responsive microgels
Resource Type
Academic Journal
Authors
王君
;
韦雄雄
;
郝红
;
王晨
;
孙瑞鸿
;
杜鲜萍
;
WANG Jun
;
WEI Xiong-xiong
;
HAO Hong
;
WANG Chen
;
SUN Rui-hong
;
DU Xian-ping
Source
化学工程 / Chemical Engineering
. 46(12):42-46
Subject
AAPBA
乳液聚合
微凝胶
葡萄糖敏感性
Language
Chinese
ISSN
1005-9954
Online Access
Scopus
Find it @ DONGA
초록
以3-氨基苯硼酸(AAPBA),N,N'-二甲基丙烯酰胺(DMAA),丙烯酰胺(AAm)为单体,N,N-亚甲基双丙烯酰胺(MBA)为交联剂,十二烷基硫酸钠(SDS)为表面活性剂,过硫酸钾(KPS)为引发剂,70℃下经乳液聚合制备了P (AAPBA-DMAA-co-AAm)微凝胶.采用FTIR,SEM和TG对微凝胶的化学结构、表面形貌和热稳定性进行了表征,粒径测试得出微凝胶的粒径分布均匀、分散性良好.通过称量法和吸光度法对微凝胶的葡萄糖响应性进行了测试.模拟人体环境进行响应实验,表明微凝胶的响应速率随着葡萄糖浓度的增加而增大,约10 min达到平衡,且具有良好的响应重现性.微凝胶对葡萄糖的快速响应为微凝胶用于药物释放体系奠定了基础.
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