早发性卵巢功能不全(POI)是一类严重影响育龄期女性身心健康的疾病,POI的病因不明.而现有研究发现,抑郁可以破坏患者的卵巢功能,增加女性早发性卵巢功能不全的发病风险.随着年龄增长,许多育龄期女性对于抑郁的易感性和情感脆性明显增高,更容易表现出抑郁症状,也更容易发生POI.但抑郁对POI发病的具体影响尚不明确,文章结合现代医学与传统医学,分别从现代研究和中医论证两方面展开论述,讨论抑郁对于POI发病机制可能造成的影响以及抑郁合并POI的治疗策略.
Early-onset ovarian insufficiency is a kind of disease that seriously affects the physical and mental health of women of childbearing age.In the hormonal fluctuation phase,women have significantly increased vulnerability to depression,and are more likely to show depressive symptoms.And existing research has found that depression can destroy the ovarian function of patients and increase the risk of POI in women of childbearing age,but the specific impact of POI pathogenesis is not clear,this paper combined modern medicine and traditional Chinese medicine and discussed the possible impact of depression on the patho-genesis of POI from the perspectives of modern research and traditional Chinese medicine as well as the treatment strategies for depression combined with POI.