目的 探讨CO2点阵激光治疗眶下皱纹的疗效和不良反应.方法 对21例有眶下皱纹的女性美容就医者给予CO2点阵激光治疗1次,能量20~30 mJ,覆盖率10%~15%.分别于治疗前、治疗后1个月和治疗后6个月拍摄标准化照片,并评价皱纹改善程度:1级(无改善或加重),2级(改善1%~25%),3级(改善26%~50%),4级(改善51%~75%),5级(改善76%~100%).使用视觉模拟评分法(0~~10分)进行疼痛评分,并观察记录色素沉着等不良反应.结果 治疗后1个月时,3级改善7例(33.3%),2级改善9例(42.9%);6个月时,3级改善9例(42.9%),2级改善8例(38.1%),与1个月对比差异无统计学意义(P>0.05).总满意度为81.0%.疼痛评分平均为(4.24±1.73)分,7例(33.3%)发生色素沉着并于3个月内消退,所有美容就医者均无瘢痕形成.结论 单次CO2点阵激光治疗能一定程度地改善眶下皱纹,不良反应轻.
Objective To investigate the efficacy and side effects of carbon dioxide (CO2) fractional laser for the treatment of suborbital wrinkles.Methods Twenty-one female patients with suborbital wrinkles received a single treatment of CO2 fractional laser at fluences of 20-30 mJ with density of 10 %-15 %.Patients were photographed standardly and evaluated at baseline,one and six months after the treatment.Wrinkle improvements were graded in 5 levels:1 (no improvement or worse),2 (1% 25% improvement),3 (26%-50% improvement),4 (51%-75% improvement),and 5 (76%-100% improvement).Patients rated the pain intensity by a visual analog scale (VAS,0 10).The side effects,such as hyperpigmentation,were observed and recorded.Results After one month follow-up,3-level improvement was observed in 7 patients (33.3%),2-level in 9 patients (42.9%);and after six months,3-level improvement was observed in 9 patients (42.9%),2-level in 8 patients (38.1%),but there was no statistically significant difference between one month and six months (P >0.05).The overall patient satisfactory rate was 81.0%.The average pain of VAS was 4.24± 1.73,7 patients (33.3%) had hyperpigmentation which faded within three months,and no patients had scars.Conclusions Single CO2 fractional laser treatment can improve the suborbital wrinkles in a cerrain extent with few side effects.