抑郁障碍是全球主要的精神健康问题之一,特殊营养成分如氨基酸、维生素、脂肪酸、益生菌等会影响抑郁障碍患者的情绪状态和疾病转归.氨基酸如色氨酸、S腺苷甲硫氨酸已经被证实可以通过多种机制改善抑郁障碍,维生素B以及维生素C改善抑郁障碍患者的应激水平进而改善抑郁症状,而不饱和脂肪酸、益生菌也被证实可以发挥同样的作用.本文对这些营养成分改善抑郁障碍的机制予以综述,以期为抑郁障碍患者治疗提供新的思路.
Depression disorder(DD)is one of the major mental health problems worldwide,and special nutrients such as amino acids,vitamins,fatty acids,probiotics,etc.can affect the emotional state and disease prognosis of DD patients.Amino acids such as tryptophan and S-adenosylmethionine have been shown to improve stress levels in DD patients through various mechanisms,including vitamin B and vitamin C,while unsaturated fatty acids and probiotics have also been shown to have the same effect.This article reviews the mechanisms by which these nutrients improve DD,with the aim of providing new clues for treatment of DD.