糖尿病下肢动脉硬化闭塞症(Diabetic lower limb arteriosclerosis obliterans,DLASO)是糖尿病患者足溃疡甚至截肢的重要原因,预后极差.目前我国DLASO患病率呈现上涨趋势.现代医学以治疗基础病、对症治疗为主要方向,尚无特效的针对性治疗手段.传统中医药以辨证论治为主.随着中药药物化学分析、药理机制研究的不断深入,中药整体调节及多靶向的治疗机制展现出了独有特色和优势.因此中药预防及治疗DLASO越来越受到重视.此文就近年来中西医治疗DLASO的进展进行综述.
Diabetic arterial occlusive disease of lower extremities,that is,diabetic lower limb arteriosclerosis obliterans(DLASO),is an important cause of foot ulcer and even amputation,and the prognosis is very poor.At present,the prevalence rate of DLASO in pa-tients with diabetes in China is still on the rise,and modern medicine focuses on the treatment of basic diseases and symptomatic treat-ment,and there is no specific and targeted treatment.Traditional Chinese medicine is mainly based on syndrome differentiation and treatment.With the deepening of chemical analysis and pharmacological mechanism research of traditional Chinese medicine,the overall regulation and multi-targeted treatment mechanism of traditional Chinese medicine show unique characteristics and advan-tages.Therefore,traditional Chinese medicine has been paid more and more attention to the prevention and treatment of DLASO.This paper reviews the progress of integrated traditional Chinese and western medicine in the treatment of DLASO in recent years.