We present a numerical study of emulsions in homogeneous and isotropic turbulence at $Re_\lambda=137$. The problem is addressed via Direct Numerical Simulations (DNS), where the Volume of Fluid (VOF) is used to represent the complex features of the liquid-liquid interface. We consider a mixture of two iso-density fluids, where fluid properties are varied with the goal of understanding their role in turbulence modulation, in particular the volume fraction ($0.03<\alpha<0.5$), viscosity ratio ($0.01<\mu_d/\mu_c<100$) and large scale Weber number ($10.6