We study the flavor-changing bottom quark radiative decay $b \to s \gamma$ induced at one-loop level within the minimal gauged two-Higgs-doublet model (G2HDM). Among the three new contributions to this rare process in G2HDM, we find that only the charged Higgs $\mathcal{H^\pm}$ contribution can be constrained by the current global fit data in $B$-physics. Other two contributions from the complex vectorial dark matter $\mathcal{W}$ and dark Higgs $\mathcal{D}$ are not sensitive to the current data. Combining with theoretical constraints imposed on the scalar potential and electroweak precision data for the oblique parameters, we exclude mass regions $m_{\mathcal{H}^\pm} \lesssim 250$ GeV and $m_{\mathcal{D}} \lesssim 100$ GeV at the 95\% confidence level.
Comment: 35 pages, 8 figures