Flaxseed Supplementation in Metabolic Syndrome Management: A Pilot Randomized, Open-labeled, Controlled Study
- Resource Type
- Authors
- Azita Hekmatdoost; Hossein Poustchi; Zahra Yari; Mehran Rahimlou
- Source
- Phytotherapy Research. 30:1339-1344
- Subject
- 0301 basic medicine
Pharmacology
medicine.medical_specialty
030109 nutrition & dietetics
Waist
business.industry
030209 endocrinology & metabolism
medicine.disease
Obesity
Clinical trial
03 medical and health sciences
0302 clinical medicine
Insulin resistance
Blood pressure
Endocrinology
Internal medicine
Medicine
Metabolic syndrome
Young adult
business
Body mass index
- Language
- ISSN
- 0951-418X
The aim of this study was to evaluate the efficacy of flaxseed supplementation plus lifestyle modification in comparison with lifestyle modification alone in the management of metabolic syndrome (MetS). A randomized controlled clinical trial was conducted on 44 patients with MetS. Participants were assigned to receive either the lifestyle advice and 30-g brown milled flaxseed daily or only the lifestyle advice as the control group. The percentage of individuals with MetS decreased from baseline by 50% and 82% in the control and intervention group, respectively. The reversion rate of central obesity was higher in the flaxseed group (36%) than control group (13%). Moreover, greater reduction in insulin resistance was observed in flaxseed group in comparison with control group (p