Sup Fig 1 from Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy
Figure S1: Functional network of the 84 ADT-RS genes, with significant interaction with ADT, revealing high degree of connectivity for some ADT-RS genes like REST and EZH2, and several pathways potentially involved in ADT resistance mechanism. SOX2 and NANOG are key transcription factors regulating many ADT-RS genes.