The aim of this study was to perform a preliminary chemical and physical characterization of the Carignano wine, an Italian monovarietal red wine mainly produced in the south-west of Sardinia (Italy). Technological parameters (alcohol, reducing sugars, total and volatile acidity, and pH), organic acid content, CIE L*C* ab h° ab chromaticity coordinates , phenolic compound contents (with spectrophotometric assays and HPLC-DAD), nitrogen compounds (with HPLC-FLD) and antioxidant capacity assessed by FRAP and DPPH assays were evaluated in 14 samples (vintage 2013) and compared with 3 aged samples. Carignano wines showed a significant level of phenolic compounds (2023 ± 435 mg GAE/L) and a good in vitro antioxidant capacity (31.6 ± 5.2 mmol Fe 2+ /L and 10.0 ± 1.4 mmol TEAC/L, respectively). The content of total polyphenols correlated significantly (p