Human brain meningioma tumor detection using visible resonance Raman spectroscopy
- Resource Type
- Authors
- Shengjia Zhang; Yan Zhou; Liang Zhang; Binlin Wu; Ke Zhu; Xinguang Yu; Robert R. Alfano; Cheng-hui Liu
- Source
- Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX.
- Subject
- Pathology
medicine.medical_specialty
business.industry
Resonance Raman spectroscopy
Healthy tissue
Human brain
Optical Biopsy
medicine.disease
Tumor margin status
Meningioma
Tumor detection
medicine.anatomical_structure
Medicine
Tumor removal
business
- Language
Meningiomas are the most common brain neoplasms. They often show a wide distribution of locations and morphological attributes. Therefore, rendering tumor margin status is difficult during surgery. Accurate identification of tumor boundary intraoperatively is essential for total tumor removal and adjacent healthy tissue preservation. Visible resonance Raman (VRR) spectroscopy has been used for detection and diagnosis of human organ lesions since 2011. Here, we report for the first time the preliminary results on the evaluation of a VRR-LRRTM analyzer based on VRR technique to identify human brain meningioma grades and margins.