ChemInform Abstract: Hydrolytic and Reductive Action of Fermenting Yeast on a Keto Acetate: Synthesis of (+)-endo-Brevicomin
- Resource Type
- Authors
- Stefano Servi; Giuseppe Pedrocchi-Fantoni
- Source
- ChemInform. 22
- Subject
- Acetate synthesis
chemistry.chemical_compound
Hydrolysis
chemistry
Stereochemistry
organic chemicals
Diol
polycyclic compounds
heterocyclic compounds
Fermentation
General Medicine
Enantiomeric excess
Yeast
- Language
- ISSN
- 0931-7597
The keto acetate 1 in fermenting yeast gives the diol 2 with high enantiomeric excess. The product arises from hydrolysis–reduction and is transformed into (+)-endo-brevicomin. The hydroxy acetate from direct reduction of 1 is racemic.