Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide Vasopressin V1b receptor antagonists
- Resource Type
- Source
- Bioorganic & Medicinal Chemistry Letters. 21:3813-3817
- Subject
Male Hypothalamo-Hypophyseal System Vasopressin Stereochemistry Clinical Biochemistry Pharmaceutical Science Biochemistry Chemical synthesis Inhibitory Concentration 50 Structure-Activity Relationship chemistry.chemical_compound Acetamides Drug Discovery Animals Humans Rats, Wistar Receptor Molecular Biology Quinazolinones ADME Arginine vasopressin receptor 1B Molecular Structure Aryl Organic Chemistry Rats chemistry Molecular Medicine Caco-2 Cells Selectivity Antidiuretic Hormone Receptor Antagonists Acetamide - Language
- ISSN
- 0960-894X